Which organ is primarily affected by hemochromatosis due to excess iron storage?

Hemochromatosis is a condition characterized by the excessive accumulation of iron in the body, which primarily affects the liver. The liver is crucial in iron metabolism and storage; when iron levels exceed the liver's storage capacity, it leads to damage and dysfunction. Over time, excessive iron can cause liver inflammation, fibrosis, and even cirrhosis. The liver not only stores iron but also plays a vital role in synthesizing proteins involved in iron regulation. Therefore, it is the organ most commonly impacted in individuals suffering from hemochromatosis, reflecting the condition's direct relationship with iron overload. Understanding this association highlights the importance of monitoring liver function in patients with excessive iron levels.